BigTTony You will get the best shot at the ratio that lets the coffee extract fully, as long as it is concentrated enough for your taste. That might be 1:2 for more soluble beans, it might be a longer ratio for less soluble beans.
You shouldn’t need to extend the shot time for longer ratios, as the larger amount of water pushed through the puck will be very effective at lifting extraction. Grinding too fine, to push up the extraction time, can have the opposite effect and reduce permeability of the puck & extraction. Or, not raise extraction significantly and just make shots unnecessarily silty.
So, if you are happy with the concentration at 22:60g, I’d use this as default. If shots have a flat/silty/muddled/muddy character, try shortening the ratio to restore clarity & intensity.